Hartono, Hartono and Azis, Andi Asmawati (2021) Cellular Function of Nuclear Pore Complex Proteins During Cell Mitosis. In: UNIVERSITAS NEGERI MAKASSAR BERLAYAR DAN BERTRANSFORMASI: 60 Pemikiran untuk Indonesia yang Berdaya Saing. Badan Penerbit UNM, Gedung Perpustakaan Lt. 1 Kampus UNM Gunungsari Jl. Raya Pendidikan 90222, pp. 245-254.
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Text (Book Chapter)
2021 Book Chapter Cellular Function of Nuclear Pore Complex Proteins During Cell Mitosis.pdf Download (464kB) |
Abstract
Nuclear pore complexes (NPCs), located on nuclear membranes of mammalian cells, are the main structure for molecular transport between cytoplasm and nucleus. These complexes are built by proteins called Nucleoporins (Nups), which vary depending on their molecular weight. Besides for transport, several Nups such as Rae1, Nup88, Nup358, Tpr, Nup62 and Nup58 have shown their roles in mitotic processes. In this article we review the structure of Nups, the process of cell mitosis, and how Nups involve in the process. Immunostaining examination showed that several nucleoporins such as Nup62 and Nup58 localize at the centrosome and mitotic spindle during mitosis. In addition, Nup58 is also found in midbodies. We conclude that Nups have important role in mitosis and cytokinesis.
| Item Type: | Book Section |
|---|---|
| Subjects: | FMIPA |
| Depositing User: | Dr Muhiddin Palennari |
| Date Deposited: | 22 Jun 2023 06:58 |
| Last Modified: | 22 Jun 2023 07:16 |
| URI: | http://eprints.unm.ac.id/id/eprint/31050 |
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