Antibacterial Activity of Secondary Metabolite Compounds in Ethyl Acetate Extract of Rumput Mutiara (Hedyotis corymbosa (L.) Lamk)

Salempa, Pince and Muharram, Muharram and Fajri, Rika (2019) Antibacterial Activity of Secondary Metabolite Compounds in Ethyl Acetate Extract of Rumput Mutiara (Hedyotis corymbosa (L.) Lamk). Materials Science Forum, 967. pp. 38-44. ISSN 0255-5476

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Abstract

Abstract: Plant Rumput Mutiara (Hedyotis corymbosa (L.) Lamk) is one of the family species of Rubiaceae which is used as a traditional medicine that is effective in healing boils, acne, antiinflammatory, and anticancer. Research methods include maceration, fractionation, purification, class test and bioactivity test with Kirby-Bauer diffusion method using Escherichia coli (E.coli) bacteria. The results of this research are pure isolates with white crystal needle shape with melting point 137-138oC. Pure isolates were analyzed using FTIR, and by the IR spectrum which showed the absorption band at wave numbers 3435.22 cm-1 indicated the presence of –OH, CH3 and -CH2-aliphatic groups (2956.87 cm-1; 2935.66 cm-1; 2893.22 cm-1; and 2866.22 cm-1), C = C (1641.42cm-1),-CH3 and -CH2- bending (1462.04 cm-1 and 1377.17 cm-1), CO (1056.99 cm-1), and = CH (964.41 cm-1). Based on the result, it showed that the isolate was a steroid group which has low antibacterial activity against E.coli with inhibition power of 10 mm.

Item Type:	Article
Uncontrolled Keywords:	Isolation, Hedyotis corymbosa(L.) Lamk, steroid, antibacterial, E.coli.
Subjects:	KARYA ILMIAH DOSEN Universitas Negeri Makassar > KARYA ILMIAH DOSEN
Divisions:	KOLEKSI KARYA ILMIAH UPT PERPUSTAKAAN UNM MENURUT FAKULTAS > KARYA ILMIAH DOSEN KARYA ILMIAH DOSEN
Depositing User:	S.T., M.T. Faruq Ratuhaji
Date Deposited:	18 Feb 2020 01:27
Last Modified:	26 Jan 2021 07:13
URI:	http://eprints.unm.ac.id/id/eprint/17112

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